What Is Frontline Plus for Dogs?
Discover how Frontline Plus for Dogs protects against fleas and ticks in the U.S. Learn application tips, safety information, and how it compares to other pet care brands.
Frontline Plus for Dogs is a veterinarian-recommended, topical flea and tick treatment designed to protect your pet for up to 30 days. It contains two active ingredients:
Fipronil: kills adult fleas and ticks
(S)-methoprene: prevents flea eggs and larvae from developing
This dual-action formula provides complete pest control, targeting fleas at every life stage.
How It Works
After application:
The product spreads across your dog’s skin and hair follicles
It starts killing adult fleas within 4 hours and ticks within 12 hours
Provides continuous protection for up to one month, even after bathing
Frontline Plus is waterproof after 24 hours and remains effectiveafter swimming or shampooing.
Benefits of Frontline Plus for Dogs
Kills fleas, flea eggs, lice, and ticks (including those that may carry Lyme disease)
Prevents future infestations by breaking the flea life cycle
Safe for dogs and puppies 8 weeks and older, including breeding, pregnant, or lactating dogs
Easy-to-use topical application once a month
How to Apply
Choose the correct dosage based on your dog’s weight (small, medium, large, extra-large)
Open the applicator and part your dog’s fur between the shoulder blades
Apply directly to the skin in one spot
Do not bathe for 24 hours post-application
Always read package directions carefully and consult your veterinarian if you have concerns.
Potential Side Effects
While generally safe, some dogs may experience:
Mild skin irritation at the application site
Excessive scratching or licking
Temporary hair loss in rare cases
Call your vet if symptoms persist or worsen.