Understanding Chronic Migraines
Learn which migraine relief treatments are most effective in the U.S. From prescription medications to holistic strategies, discover how to manage chronic migraine pain long-term.
Chronic migraines affect more than 4 million Americans, often occurring 15 or more days per month, with at least 8 days of migraine symptoms. They can be debilitating, leading to missed work, social isolation, and a reduced quality of life.
Fortunately, new therapies and updated clinical guidelines offer more targeted and effective treatment than ever before.
Top Chronic Migraine Treatment Options in the U.S.
1. Prescription Preventive Medications
These are taken regularly to reduce frequency and intensity of migraines.
CGRP inhibitors (like Aimovig, Emgality, Ajovy)
Beta blockers (like propranolol)
Anti-seizure drugs (like topiramate)
Antidepressants (such as amitriptyline)
These medications are often FDA-approved for chronic migraine prevention.
2. Abortive Medications
Used at the onset of symptoms tostop a migraine attack.
Triptans (e.g., sumatriptan)
Ditans (e.g., Reyvow)
Gepants (e.g., Ubrelvy, Nurtec)
NSAIDs (e.g., naproxen)
Fast-acting abortive therapy can dramatically reduce downtime.
3. Botox Injections
FDA-approved for chronic migraine in the U.S.
Administered every 12 weeks across 31 specific head and neck injection sites
Reduces headache frequency by paralyzing pain-related nerves
4. Neuromodulation Devices
Wearable devices like Cefaly or gammaCore
Use electrical or magnetic stimulation to target migraine-related nerves
Non-invasive and often used with or without medication
5. Lifestyle and Natural Therapies
Magnesium, riboflavin, and CoQ10 supplementation
Yoga, meditation, and cognitive behavioral therapy
Diet modifications (avoiding trigger foods like caffeine, MSG, alcohol)
When to See a Specialist
If you:
Have headaches more than 8 days/month
Experience aura, nausea, light sensitivity
Aren’t responding to OTC medications
Miss work or social events frequently due to migraines
...it’s time to consult a neurologist or headache specialist. They can personalize a plan using combination therapy, tailored to your symptoms and triggers.